No, Frontline Plus is only for use on cats and should never be used on dogs. It contains fipronil and (S)-methoprene, which are toxic to dogs and can cause serious side effects including trembling, seizures, vomiting, and death.
If you need flea and tick protection for your dog, talk to your veterinarian about dog-safe products such as Seresto collars, Trifexis, Nexgard, or Frontline Tri-Act Plus.