Why Do Lips Go Numb After Eating Puffer Fish?

Puffer fish, also known as blowfish or fugu, contain a deadly neurotoxin called tetrodotoxin. This toxin can cause numbness of the lips, tongue, and throat, and in severe cases, paralysis and respiratory failure.

Where the Toxin Is Found

Tetrodotoxin is concentrated in the liver, intestines, and gonads of puffer fish. When the fish is eaten, the toxin can be absorbed into the body through the digestive tract. Symptoms may begin within minutes or hours.

Numbness as an Early Symptom

Numbness of the lips is a common early sign of tetrodotoxin poisoning. It occurs because the toxin affects the nerves supplying the lips. As it spreads, numbness may also develop in the tongue, throat, and face.

Other Symptoms

In addition to numbness, tetrodotoxin poisoning can cause:

Difficulty breathing
Nausea and vomiting
Diarrhea
Abdominal pain
Headache
Dizziness
Confusion
Seizures
Paralysis

Medical Emergency

Tetrodotoxin poisoning is a medical emergency. If you suspect you have been poisoned by tetrodotoxin, seek medical attention immediately.